vivoPHIX™, genoPHIX™ and virusPHIX™
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Single-cell RNA sequencing presents an opportunity to deconstruct cellular networks but is limited by the loss of biological information. In this study, a new method of fixation before dissociation using a deep eutectic solvent (DES) is presented.
This research paper used the RNAssist’s vivoPHIX™ system to examine the intricacies of insect innate immunity. Sarah Merkling et al., aimed to gain a deeper understanding of the immune responses in insects at the level of specific organs and cell populations, with the goal of improving our overall knowledge of tissue- or cell-specific immune processes across species and facilitating the creation of models for predicting within-host infection dynamics.
RNAssist fixed mouse liver, paraffin embedded, stained with RNAscope® probe PPIB. Thanks to Bingqing Zhang, ACD™, Bio-techne.
genoPHIX™ is for fixing and paraffin embedding tissue sections for a variety of histology applications including H&E staining, ISH, FISH, IHC and Immunofluorescence.
RNAssist technology supports a wide range of life science applications, including tissue fixation and dissociation, single-cell multiomics (scRNA-seq, CITE-seq), and virus inactivation and transport for enhanced diagnostic testing.
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